In the eukaryotic chemosensory signaling circuit, attractant signals sensed by cell-surface receptors are amplified by a positive feedback loop at the leading edge of the cell. The feedback loop, in ...

A deeper look at the basis of coincidence detection revealed a circuit between Netrin-1-Dcc signaling and two other proteins, Pard3 and JamC. These give Dcc clustering and adhesion cues at sites ...

David Solecki, PhD, St. Jude Department of Developmental Neurobiology identified a “coincidence detection circuit” responsible for the migration of mature neuronal cells from the germinal zone ...

It also means it is straightforward enough to use with other software as well, like integrating LTspice with Python for some interesting signal processing circuit simulation. [Michael]’s latest ...

Integrated circuits (IC) serve as the backbone of any information system and mobile devices. This course provides an in-depth review of the advanced technology in ...

“This opens up the signaling circuit design space dramatically,” said Caleb Bashor, an assistant professor of bioengineering and biosciences and corresponding author on the study. “It turns out, ...

Each protein component of the circuit serves as an on-off switch that controls the activity of the next component in the pathway, and the output signal of the curcuit ultimately regulates the motility ...