However, these activated receptors also signal from endosome membranes, where they can physically interact with some of their downstream signaling factors. In animals, researchers first realized ...

Ubiquitylation is the best characterised signal for entry into this pathway ... which are enriched in early endosome membranes. ESCRT-I is built around a heterotrimeric core to which flexibly ...

It plays a key role in nutrient absorption, immune defense, signal transmission ... which plays a vital role in regulating endosome maturation. This gene encodes a deubiquitinating enzyme that ...