另外除了数据库验证，研究者利用空间单细胞蛋白组平台COMET在肺腺癌和胰腺癌中也进行验证。20-plex抗体检测肺腺癌，17-plex抗体检测胰腺癌。结果与CosMx/MERSCOPE转录组结果一致，证实四种CAF亚型的跨技术可重复性，将转录组定义的亚型锚定到具体组织学结构中。

Researchers are studying why the energy factories are moving between cells and whether the process can be harnessed to treat ...

A study by scientists at the Herbert Irving Comprehensive Cancer Center (HICCC) introduces a more cost-effective, scalable ...

2025年3月26日，上海市肺科医院陈昶教授与北京大学生物医学前沿创新中心张泽民院士等合作团队，在国际期刊Cell上以Resource形式在线发表了题为“A single-cell atlas reveals immune heterogeneity in anti-PD-1-treated non-small cell lung cancer” 的研究论文。陈昶教授及胸外科佘云浪副研究为该论文的 ...

Researchers from Tel Aviv University have developed an innovative method that can help to understand better how cells behave in changing biological environments, such as those found within a cancerous ...

A University of Iowa-led study has revealed the unexpected structure adopted by the DNA repair protein RAD52 as it binds and ...

Single-cell gene sequencing has changed the way scientists understand life at the smallest level. It lets researchers study ...

Explore a high-throughput picodroplet-based method for CAR-T cell functional validation that enables rapid, single-cell ...

This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

Single-cell characterization of healthy fallopian tubes revealed shifts in cell and gene expression throughout the menstrual ...