Alzheimer’s disease is notorious for robbing individuals of memory and cognitive function. Researchers have struggled for ...

If drugs could be developed to prevent orexin from binding to its receptors, Mignot thought, then people with insomnia would become “narcoleptic for one night”. In 2007, researchers at the ...

The use of AI in sleep medicine continues to evolve, said D’Ambrosio. She cited a recent review in the Journal of Clinical ...

Analysts at BMO Capital Markets said Centessa’s orexin receptor agonist has “best-in-class” potential for narcolepsy, putting ...

Idorsia has become the first drugmaker in the EU to claim approval for a drug for chronic insomnia in the dual orexin receptor antagonist class, ahead of rival drugs from Merck & Co and Eisai.

The orally-active drug was granted breakthrough status by ... reinforcing the role of orexin in sleep pathways. "We are working to quickly assess the totality of available data to inform the ...