A team of Chinese researchers led by Prof. WANG Likun from the Institute of Biophysics of the Chinese Academy of Sciences has provided new insights into metabolic disease mechanisms and potential ...

As a central molecule in the sphingomyelin metabolic pathway, ceramide is closely associated with metabolic disorders such as diabetes, obesity, and atherosclerosis. Current research has revealed ...

The researchers eventually homed in on sphingomyelin-ceramide metabolism, one of the pathways these peaks represented (Nat Chem Biol, 8:232-34, 2012). But what about the compounds they didn’t pursue?

These findings advance the understanding of ceramide's biological functions and open new avenues for developing targeted therapies against metabolic diseases. As a central molecule in the ...