Patients who used statins had a reduced risk for HCC, hepatic decompensation and fibrosis progression. Lipophilic statin use and longer duration of exposure were associated with even greater ...

Background: Statins are generally well tolerated, but some patients discontinue therapy secondary to adverse effects. Dosing a statin (rosuvastatin) every other day (EOD) may provide significant ...

However, many current statins have major limitations. Moreover, innovative treatments need to address non-LDL-C residual risk (which may be marked by high triglycerides, low HDL-C concentrations ...