Statin therapy has proven efficacy for reducing the incidence of major adverse clinical events, but when administered in high doses these agents can cause myopathy. A means to identify those at ...

Pharmacogenomics. 2012;13(7 ... revealed several genetic variants associated with variation in response to statin therapy. Important genes involved in the lipid-lowering response to statin ...

The majority of the total heritability of CAD is still unexplained and risk prediction models may be improved with the addition of contributing effects ... SLCO1B1 gene are at increased risk for ...