The complexity of bone marrow has made it difficult for researchers to duplicate ex vivo the conditions encountered by stem cells in vivo. As a result, explanted HSCs lose their pluripotency and ...

The Stem Cell Core provides access to a streamlined, IRB-approved consenting process for acquisition of patient samples and generation of pluripotent stem cells and stem cell-derivatives for basic and ...

Jacob Hanna, a stem cell biologist at the Weizmann Institute of Science, wanted to know why this transition occurs. To answer this question, Hanna and his team set out to develop an ex utero embryo ...

Using Cas9, the authors restored dysferlin in muscle stem cells from patients ex vivo and show proof-of-concept for autologous cell replacement therapies in a new humanized mouse model.