Researchers explore how natural compounds in traditional Chinese medicine can modulate cholesterol metabolism to combat ...

A bacterium makes a molecule that kills drug-resistant fungi in an unusual way — by targeting various phospholipid molecules in membranes.

More information: Kelly M. Frain et al, Conformational changes in the Niemann–Pick type C1 protein NCR1 drive sterol translocation, Proceedings of the National Academy of Sciences (2024). DOI ...

Trimerization of commercially available coprostanone (a steroid ketone with a cis A/B ring junction) by treatment with titanium tetrachloride yields this unusual, chiral, cleft-containing molecule.