Recent work has shown us that G3BP nucleation of stress granules in the absence of virus infection activates PKR, resulting in phosphorylation of eIF2alpha and activation of NF-kB and JNK signal ...

We are interested in mechanisms that regulate RNA Stress Granule (SG) and Processing Body (P-body ... and function by through the SG and P-body pathways. We found that poliovirus 3Cpro cleaves a ...

The researchers found that the ZO-1 protein directs YB-1 to form beneficial stress granules. Stress granules are clusters of proteins that assemble inside cells exposed to stressful conditions ...

A protein was created where TDP-43 was fused to the SUMO2 protein and these fusion proteins were expressed in cells with or ...