We are interested in mechanisms that regulate RNA Stress Granule (SG) and Processing Body (P-body) formation in cells. These two types of RNA granules aggregate translationally-silenced mRNAs and ...

This could be a major function of stress granules that all viruses must counteract to effectively replicate. We have also shown that expression of the P-body component Dcp1a results in activation of ...

The researchers found that the ZO-1 protein directs YB-1 to form beneficial stress granules. Stress granules are clusters of proteins that assemble inside cells exposed to stressful conditions ...