Electrophysiological studies, as well as light, fluorescence and electron microscopy approaches, have advanced our understanding of the functional and morphological characteristics of synaptic ...

A new Drosophila collection of Parkinsonism models reveals early synaptic cholinergic projection neuron dysfunction, linking synaptic failure to later dopaminergic decline, highlighting a role for ...

By influencing calcium homeostasis, local protein synthesis and the endoplasmic reticulum, a small protein called Rab10 emerges as a crucial cytoplasmic regulator of neuropeptide secretion.

This was achieved through adjusting the resistance of the bulk terminal to specific values ... capable of operating either in a neuron or a synaptic regime, which the researchers have called ...