In T cell cancers such as T cell lymphoblastic leukemia (TLL), this challenge arises from fratricide, CAR T cell self-destruction. 1–3 CAR T cells often share the same receptors as malignant T cells, ...

B-cell prolymphocytic leukemia (B-PLL) is a rare, aggressive type of leukemia that progresses rapidly. People with B-PLL typically have a less favorable outlook. However, new targeted treatments ...

Patients with acute myeloid leukemia who relapse after stem cell transplantation have just a small chance of survival: doctors can give them additional donor T cells to fight the cancer, but only ...