Zelluna (OSE: ZLNA), a company pioneering allogeneic ‘off the shelf’ T Cell Receptor based Natural Killer (TCR-NK) cells for ...

5 (4) A CAR controlled remotely via drugs and other small molecules puts the brakes on T cell activation and prevents exhaustion. 6,7 (5) The T cell receptor (TCR) is a protein complex that recognizes ...

推荐语：本研究揭示了TCR-pMHC-CD8三分子复合物在机械力调控下的"捕获-滑动"键动态特性，解决了高亲和力TCR工程中自身肽交叉反应性的难题。作者通过单分子生物力学、MD模拟等技术，发现CD8通过力依赖的构象变化增强TCR对激动肽的识别，而过度强化的TCR-pMHC结合 ...

TScan Therapeutics, Inc. (Nasdaq: TCRX), a clinical-stage biotechnology company focused on the development of T cell receptor (TCR)-engineered T cell (TCR-T) therapies for the treatment of patients ...

Following the insolvency filing, Medigene AG is exempt from the obligation to convene an extraordinary shareholder meeting according to § 92 German Stock Corporation Act (AktG).

The advent of T-cell receptor (TCR) sequencing offers a transformative lens to unravel these challenges, spotlighting tumor-immune interactions and adaptive immune mechanisms pivotal to advancing ...

Immunocore Holdings' stock has dropped 60% as Kimmtrak faces market saturation, but its pipeline could offer potential. Find ...

In a phase 1 trial involving 40 patients, the research group investigated the use of T cell receptor (TCR)-engineered T cells. Using genetic ...

Immatics N.V. (NASDAQ: IMTX, “Immatics” or the “Company”), a clinical-stage biopharmaceutical company active in the discovery ...

In the study, "Disease diagnostics using machine learning of B cell and T cell receptor sequences," published in Science, researchers analyzed BCR heavy chain and TCR beta chain sequences from 593 ...

Zelluna Reaches Major Milestone with Manufacturing Process Established in Preparation for Clinical Entry of ZI-MA4-1, its Novel TCR-NK Therapy Targeting Solid Tumours Oslo, Norway, 22 April 2025 – ...

IMA203 is an autologous, engineered T-cell receptor T-cell therapy (TCR T) that targets PRAME, an intracellular protein displayed as a peptide antigen on the surface of multiple solid tumors via ...