Transforming growth factor β1 (TGF-β1), a key regulator of the brain's responses to injury and inflammation, has been implicated in Aβ deposition in vivo. Here we demonstrate that a modest ...

TGF-β1 and COX-2 are gatekeeper targets for oncology ... marked tumor regression through extra penetration of CD4 and CD8 positive T cells (Fig. 1). Immunohistochemistry showed the T cells ...

Secreting CXCLs, ILs, TGF-β, CCL12, PGE2, CAFs promote pro-cancer macrophage conversion, inactivate NK cells, and hinder CD8+T cell aggregation. Immune cells like TAMs, NKs, CD8+Ts, MCs ...