Trial achieved key objectives for safety, tolerability, pharmacokinetics and pharmacodynamicsClinical data from this trial, ...

While the common ancestor of vertebrates with synovial joints is still a mystery, the oldest specimen with evidence of these ...

An enlarging family of matrix-metalloproteinases has ... production and contractility have been attributed to autocrine TGF-beta and endothelin-1, respectively. Stellate cells can amplify the ...

In 2019 and 2020, the researchers reported that DYRK1A inhibitors can synergize with TGF-beta signaling as well ... exciting finding that shows harmine-family drugs may be able to induce lineage ...