Thus, as with any new treatment modality, caution is required in the follow-up of patients receiving TNF blocker treatment, since new side effects and complications are continuously being reported.
The first study examines TNF-a levels in patients receiving the GLP-1 agonist Wegovy ® or Ozempic ® who show signs of increased inflammation associated with sarcopenia, which is the progressive loss ...
In fact, rates of adverse events such as respiratory hospitalization, death from lung disease, and all-cause mortality were numerically higher in the non-TNF inhibitor users -- hazard ratios ...
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Etanercept is one of the most frequently used TNF blockers, and has been approved for use in not only moderate-to-severe plaque psoriasis but also rheumatoid arthritis, polyarticular juvenile ...
TNF inhibitor users had a lower risk for hip and spine fractures (adjusted odds ratio [aOR], 0.75; 95% CI, 0.62-0.91) than NSAID users, but this protective association was not seen in csDMARD users.
Whereas the trial's original primary analysis showed roughly double the MACE risk with tofacitinib as compared with TNF blockers, when the JAK inhibitor group was stratified according to statin ...
TNF Pharmaceuticals (TNFA) announced that it has achieved a safety data milestone supporting expanded and longer-term clinical studies of its ...