Using a novel quantitative chemoproteomic strategy, a research group led by Prof. Wang Chu from the College of Chemistry and ...

Activating stem cells via molecular programming, rather than relying on random cell transplants, significantly enhances the success of regenerative treatments.

Tau is a microtubule-associated protein that ... In addition, animal models that closely mirror the initiation and progression of human tauopathies have so far been lacking. Researchers at the ...

In this new study, the research team developed a nasal spray with the ability to clear tau proteins from the brains of mice engineered to have human-like Alzheimer's symptoms. The researchers ...

Using human induced pluripotent stem cells (iPSCs), the international team has been able to show that a specific form of the tau protein, known as the 1N4R isoform, is responsible for mediating ...

The research group led by Prof. Wang Chu from the College of Chemistry and Molecular Engineering at Peking University ...

The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC-derived neurons to amyloid beta and phosphorylated tau-induced neuronal dysfunction. Alzheimer's & Dementia , 2025 DOI: 10. ...