Aortic aneurysms, known as "silent killers," are increasingly deadly, causing 2 per cent of global cardiovascular deaths ...

They can involve the ascending aorta, aortic arch, thoracic descending aorta, and/or abdominal descending aorta. Tang, Zhang, Fang, Zhu et al. identify impaired mitochondrial fusion and biogenesis ...

Mitochondrial NAD + deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm Zhang et al. demonstrate that the smooth muscle-specific ...