Four years ago, protein drug developer Zymogenetics in Seattle began developing a recombinant version of the blood-clotting protein thrombin. On 17 January, it received US marketing approval for ...

For excessive bleeding during surgery, four-factor prothrombin complex concentrate is more effective and cause fewer side ...

A major clinical trial finds prothrombin complex concentrate (PCC) is safer and more effective than frozen plasma for treating bleeding during cardiac surgery. Discover key findings and implications ...

The concentrated product, known as four-factor prothrombin complex concentrate (4F-PCC), reduced patients' risk of experiencing ... of clotting factors and their inhibitors of coagulation that help to ...