Tissue function depends on more than cell type ... Transmembrane integrin proteins in the junctions bind components of the ECM and recruit signaling proteins to their cytoplasmic sides.

A new tissue expansion method enables scientists to use mass spectrometry imaging to simultaneously detect hundreds of molecules at the single cell level in their native locations.

In this technique, when a laser beam is shined on biological tissue, the tissue components absorb the light and the tissue heats up slightly (less than 1°C). This causes the tissue to expand and ...

Precise interactions between the different tissue components are needed to maintain tissue homeostasis, and alterations in this interplay can lead to complications in tissue regeneration or to ...

Wang and her team study the fundamental mechanisms behind aging and longevity, and they wanted to detect many different biomolecules in intact tissues to understand how the components change as ...