Movement is a complex process governed by a network of neuronal circuits spread across multiple regions of the nervous system ...

Motor neurons project from the central nervous system to innervate muscle cells to either directly or indirectly control their activity. Contact between a motor neuron and muscle cell is usually ...

and central nervous system disorders, which can result in the loss of motor neurons and progressive muscle wasting. ASOs comprise a single strand of a few dozen base pairs arranged in the reverse ...