These therapies involve programming the T-cell receptor (TCR) of T cells to recognize a specific peptide, or antigen, found on tumor cells. There are many efforts underway to identify the most ...

Finally, peptide microarrays can be used for the reliable detection of autoantibodies with low serum titers, such as antibodies to tumor-associated antigens in individuals with cancer. We obtained ...

In another approach, the vaccine, which is protein-based or peptide-based, contains only the protein of the tumor antigen or at least parts of it. This synthetic method is faster, cheaper and less ...

Cryptic peptides, which are expressed in pancreatic cancer cells, could be promising targets for T-cell therapies that attack pancreatic tumors, according to a new study.

Using T cell receptor sequencing on both functionally expanded T cells and neoantigen-loaded tetramer-sorted T cells, we identified tumor antigen-specific T cell receptors,” write the investigators.

TwoStep Therapeutics is a Stanford University spin-out launched in 2024, co-founded by Nobel Prize winner Carolyn Bertozzi, ...

TPU researchers, together with their colleagues from Moscow, have succeeded in synthesizing a new generation molecule for ...