Upon being absorbed by the tumor cell, PT-112 triggers cancer cell death in such a way that the subsequent release of DAMPs promotes a tumor-specific immune response with the potential for ongoing ...

The study, published in Cancer Cell, explains how a type of cancer cell death can actually make tumors grow faster by turning off the immune system's ability to fight the cancer. Researchers at ...

As cells are infected by microorganisms, they can pre-emptively die to prevent the replication and spreading of the pathogen. Cell death that is associated with the presence of pathogen-associated ...

there is a need to understand how and why cells within a tumor embark on that journey. A study published on March 8 in Cell Reports suggests that a near-death experience may induce cancer cells to ...

Scientists are looking for answers about how these confounding trips, known as metastases, occur throughout the human body ...

Glioblastoma, one of the most aggressive and lethal brain cancers, has a five-year survival rate of only 6.9%, according to the National Brain Tumor Society. While the relationship between ...

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells overcome this effect and resist death. Sahana is a science journalist and ...

When successful, these cancer treatments cause enough DNA damage to trigger cancer cell death. However, the array of different damages potentially induced by these drugs makes it difficult to ...

This paper explores the potential of mitochondrial-associated programmed-cell-death (mtPCD) patterns as biomarkers for ...

By unveiling the complex interactions between ubiquitination, cell death pathways, and cancer biology, this review lays the foundation for novel therapeutic strategies. Genes & Diseases publishes ...