Hyundai Bioscience presented the results of its Penetrium™ combination preclinical studies at the 2025 American Association ...

The tumor microenvironment (TME) consists of a complex mix of cellular and non-cellular components, including immune cells, ...

In cancer and obstructive disease, the ECM has a critical role in pathogenesis. The challenge in these settings will be to find therapies that prevent hyperproliferation and encourage proper ...

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, ...

CAFs Impact ECM and tumor growth: CAFs secrete MMPs to degrade ECM, releasing growth factors for cancer cells. ECM changes counteract CAFs and tumor cells: (a) Hard ECM triggers Twist release from ...

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, ...

The Incucyte ® Live-Cell Analysis System is a fully automated platform for phase contrast and two-color fluorescence imaging, ...

Adhesive Interactions Influencing Metastases Integrins are the major extracellular matrix (ECM) receptors, and integrin-mediated adhesive interactions between tumor cells and the components of ...

gene—which contribute to the growth of several types of cancer—result in the overexpression of agrin in the ECM, increasing agrin's ability to support the progression of lung adenocarcinoma ...

We are especially interested in understanding the role of ECM in breast cancer initiation. To do this, we use organotypic models of human and mouse mammary epithelium and various imaging techniques to ...