Ubiquitin marks proteins for degradation, whereby ubiquitin molecules can be combined in different types and numbers forming ...

Figure 1: Discovery of the ligation of ubiquitin to lysozyme, a substrate of the proteolytic system. As indicated before 19, the main lesson from our story is the continued importance of the use ...

To prevent this, cells have developed a sophisticated system to mark unwanted proteins for degradation with a small protein called ubiquitin. Ubiquitin chains Ubiquitin is a cellular tag that marks ...

Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...