Ubiquitin and the Biology of the Cell, as the editors note, is published 10 years after the first book on ubiquitin appeared and 23 years after the first biochemical description of this ubiquitous ...

A cell signaling mechanism of fundamental importance to animal development is the Notch pathway (Figure 1). It may be safely said that Notch signaling is required, in some reasonably direct fashion, ...

The review delves into the E3 ubiquitin ligases ... between ubiquitination and key signaling pathways, including Notch, Wnt/β-catenin, Hedgehog, and Hippo-YAP, which regulate stem-like properties ...