Humans do not express urate oxidase, but species that do express it tend to have low urate levels, so Garson et al. developed a polyethylene-glycol-modified recombinant mammalian urate oxidase ...
Additionally, coffee inhibits xanthine oxidase, an enzyme involved in the ... it can cause a variety of health problems. Many urate crystals can precipitate in the joints and cause gout: a painful ...