Besides dystrophin, the study focuses on a second protein called utrophin, which is related to dystrophin. "It was already known that increased production of utrophin can at least partially ...

Ezutromid was designed to treat DMD by boosting utrophin levels to compensate for the faulty dystrophin protein that is the root cause of the very rare muscle-wasting disease. Summit reported ...

MAST205 colocalized with β2-syntrophin and utrophin at neuromuscular junctions. SAST colocalized with syntrophin in cerebral vasculature, spermatic acrosomes and neuronal processes. SAST and ...

For innovation in medicinal chemistry leading to the identification of first in class utrophin modulators for the treatment of Duchenne muscular dystrophy. Throughout this endeavour has been, and ...