Objectives: To assess the efficacy and tolerability of valsartan and valsartan plus hydrochlorothiazide (HCTZ), given alone or as part of a combination regimen with other antihypertensive agents ...

Valsartan blocks the effect of angiotensin II ... The usual dose is 80/12.5 mg, 160/12.5 mg or 320/12.5 mg once a day. If your blood pressure is still too high after 4 weeks, your doctor may ...

In another such trial (VALUE), researchers randomized 15,245 hypertensive patients (minimum age, 50; mean BP, 155/87 mm Hg) in 31 countries to receive the angiotensin-receptor blocker valsartan or ...