This mechanism, which involves extracellular accumulation of a 56 kDa soluble amyloid-β (Aβ ... Their results suggest that other soluble protein assemblies could also have a role in inducing ...

At most, we observed a slight astrocyte response using immunostaining with antibody against glia fibrillary acidic protein (data not shown). These data indicate that clearance of amyloid-β after ...

Recent approvals by the Food and Drug Administration have focused on medications that shrink the sticky brain deposits of a protein called amyloid beta. The errant growth of this protein is ...

Alzheimer’s disease is a dominant form of dementia, representing 60 to 70 percent of cases. Recent approvals by the Food and Drug Administration have focused on medications that shrink the sticky ...

It turns out that a protein we’ve been fighting against might actually be our brain’s best friend. For years, doctors blamed amyloid beta buildup in the brain for causing Alzheimer’s disease.

Alzheimer's disease is likely caused by stalled protein processing in the brain, according to a new study. For several decades, researchers studying Alzheimer's disease have been working to ...

"Aβ42 is a protein that defends our brain from ... Dwivedi, A., & Imbimbo, B. P. (2024). Increases in amyloid-β42 slow cognitive and clinical decline in Alzheimer's disease trials.

A study of rare familial genetic mutations linked to early-onset dementia supports the idea that stalled protein processing contributes to Alzheimer’s disease.

In the Journal of Clinical Investigation, January 2, scientists led by Zhifang Dong at the Children’s Hospital of Chongqing Medical University, China, report that lactate modifies specific lysines on ...