The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

The chromatin landscape is a key aspect of epigenetic regulation in eukaryotes. Old histones are recycled during DNA replication, therefore providing a blueprint for the duplication of their ...

This represents a conceptual breakthrough.Not only does it offer targets for therapy for several diseases, but we are adding ...

We specialize in high throughput top down liquid chromatography-mass spectrometry. This allows us to study chromatin biology with proteoform level specificity and observe quantitative changes to ...

Chromatin remodelers play a key role in regulating access to DNA (which is packed within the cell into chromatin), hence ...