The discovery of lysosomes led to many new questions. The most critical question was: what was the physiological function of this "bag" of enzymes? The Function of Lysosomes One of the definitive ...

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged ...

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.

The Golgi apparatus functions as a molecular assembly line ... they are directed to their appropriate destinations — either lysosomes, storage vesicles, or the plasma membrane (Figure 2).

The STING protein, known for helping cells fight viral infections by generating inflammation, also appears to function as a ...

Scientists have uncovered more than 20 genes whose mutations cause familial forms of Parkinson's disease. One of these genes ...

Kanazawa University, report in Nature Communications how the targeted suppression of lysosome function may lead to brain cancer therapy.

A new set of genes that contribute to Parkinson’s disease risk has been identified.

Evidence suggests that in Parkinson’s disease, a breakdown in lysosomal function allows lipids to build up within cells. Variants of the GBA1 gene, the strongest genetic risk factor for sporadic PD, ...

Damaged lysosomes are repaired by a lipid-based signaling pathway ... who was not involved in the study. But the pathway might function differently in other cells, including neurons, so more work is ...