The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

To analyze the success of the experiment, carry out amplification of 1–2 μl of the diluted DNA as a template, using PCR primer pairs that amplify sequences for which the histone modification ...

Discover how histone modifications unlock secrets of human aging, rivaling the precision of DNA methylation in decoding biological age. In a recent study published in the journal Science Advances ...

Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power.

The histone tag, characterized by lysine 8 acetylation on histone H4, identifies a significant departure from the histone modifications found in neonatal OPCs. Detailed in a paper published in The ...

Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, ...