Scientists have officially grown a notochord—the tissues that act as the “GPS for the developing embryo” by guiding the ...

引言每一个脊椎动物的生命起源都离不开一条神秘的“脊索”（notochord）。这根微小却至关重要的结构不仅决定了身体轴线的形成，还在胚胎发育中担负着引导周围组织分化的重任。然而，研究人员长久以来一直面临一个难题：尽管在实验室中通过多能干细胞（pluripotent stem ...

Detailed transparent video showing notochord cells (red) and the associated patterning molecules (in cyan) inside a trunk organoid. Cell nuclei in gray. Electron scanning microscopy image (2 ...

Francis Crick Institute scientists developed a rudimentary human spine via stem cells in a laboratory. They have created a “trunk-like structure” that is around 1 to 2 millimeters long. Despite its ...

Yes, according to Osaka Metropolitan University researchers, who found that suppression of Pcdh8 is essential for the notochord to elongate properly in zebrafish. Graduate School of Medicine Dr.