Lysosomes break down macromolecules into their constituent parts, which are then recycled. These membrane-bound organelles contain a variety of enzymes called hydrolases that can digest proteins ...

By 1955, additional hydrolases (enzymes that break chemical bonds ... De Duve named these new organelles "lysosomes" to reflect their lytic nature. That same year, Alex Novikoff from the ...

For instance, mitochondria generate energy by breaking down nutrients; lysosomes break down and recycle cellular components and the endoplasmic reticulum (ER) synthesizes lipids and proteins, aiding ...

Neurodegenerative diseases like Alzheimer’s and ALS involve different proteins, but they share a key problem: the proteins ...

Kanazawa University, report in Nature Communications how the targeted suppression of lysosome function may lead to brain cancer therapy.

Lysosomes are membrane-bound organelles in cells that act as recycling centers—breaking down waste materials, damaged ...

Now, Atsushi Hirao from Kanazawa University and colleagues have investigated the role of lysosomes—cellular organelles that break down biomolecules no longer needed—in metabolic processes linked to ...

These rare neurodegenerative diseases are characterized by the dysfunction of lysosomes, cellular organelles that break down various substances ready for disposal, including proteins, nucleic ...

Antimalarials go directly into these lysosomes and decrease the acid levels in there ... when you put any substance into a cell it has complicated chemical processes in place to break it down, use ...