It works by switching off nociceptors in the peripheral nervous system, and therefore preventing pain signals getting to the brain. This represents a potential new breakthrough in a world which has ...

pain was considered a physical sensation felt somewhere in the body. Research has shown that pain activates some of the same areas of the brain that handle emotions, such as the limbic system.

A network of nerves similar to wires runs all through the human body, from the tips of your fingers and toes, through your back inside the spinal cord and up to your brain. Specialized pain receptors ...

Pain is a universal human experience—essential for survival yet unbearable when it lingers unchecked. From the intensity of post-surgical recovery to the grip of chronic conditions, pain ...

A research team at the Institute of Psychology of the Chinese Academy of Sciences, has revealed that parvalbumin (PV) interneurons in the primary somatosensory cortex (S1) preferentially encode ...

Having lived with disabling chronic pain for 32 years, one reader discovered a lesser known treatment that has transformed ...

Thomas Smith, MD, Professor of Palliative Medicine & Oncology at Johns Hopkins Kimmel Cancer Center explains, “You’ve got these chronic pain signals going up your spine to your brain ...

The FDA’s nod for suzetrigine bolsters confidence in the pharmaceutical industry’s strategy to target sodium channels.

One participant in the drug trial for Journavx said it eliminated her pain without making her feel loopy or nauseous, which ...