It works by switching off nociceptors in the peripheral nervous system, and therefore preventing pain signals getting to the brain. This represents a potential new breakthrough in a world which has ...

Pain is a universal human experience—essential for survival yet unbearable when it lingers unchecked. From the intensity of post-surgical recovery to the grip of chronic conditions, pain ...

Having lived with disabling chronic pain for 32 years, one reader discovered a lesser known treatment that has transformed ...

A research team at the Institute of Psychology of the Chinese Academy of Sciences, has revealed that parvalbumin (PV) interneurons in the primary somatosensory cortex (S1) preferentially encode ...

Your brain interprets these signals to locate the ... In fact, it’s a problem if you can’t feel pain. Some people have a genetic mutation that changes the way their nociceptors function ...

The FDA’s nod for suzetrigine bolsters confidence in the pharmaceutical industry’s strategy to target sodium channels.

as seen in their behavioural ratings of pain intensity felt by others. However, the brain becomes increasingly reactive to seeing others in pain as we age, which suggests that older adults ...

One participant in the drug trial for Journavx said it eliminated her pain without making her feel loopy or nauseous, which ...