Therefore, a great deal of effort is being invested worldwide in developing therapeutic agents that function by fine-tuning the Wnt pathway. This article describes major milestones that have ...

Hypospadias is characterized by an ectopic urethral opening and abnormal penile curvature, affecting approximately 1 in 200 live male births.

ST316, a β-catenin/BCL9 antagonist, demonstrated safety, target engagement, and early antitumor activity in advanced solid ...