Study in mice and human cadavers hints that a brain-protective gene in the chromosome becomes more active with age.

The evolution of the dosage compensation mechanism is inextricably interwoven with the evolution of the mammalian sex determination system and the formation of the Y chromosome (Fig. 1).

Human biological sex is determined by the sex chromosomes X and Y. In most cases, females possess two X chromosomes, while males have one X and one Y. However, there is some evidence that the Y ...

The first full sequence of the Y chromosome contained 30 million new base pairs. Phillippy said that most of these newly discovered sequences relate to sequences on other chromosomes but carry subtle ...

This fascinating case demonstrates the resilience of nature and the ability to adapt to genetic changes. Such examples suggest that even if the Y chromosome disappears—which may take millions of ...

which are sections of DNA located at specific points on a chromosome. The Y chromosome is an exception, only containing a few dozen genes. DNA is the material carrying all the information about ...

When Nettie Steven discovered the Y chromosome in 1905 while studying the mealworm Tenebrio molitor, she identified it as a sex-determining chromosome. As it turns out, the chromosome also has ...

Why losing the Y chromosome is more than genetics—it’s a key to understanding male health disparities. In a recent review article in the journal Nature Reviews Genetics, researchers discussed ...

If this hereditary tradition has been closely followed, the Y chromosomes of the Cohanim today should bear some resemblance to one another because of their unbroken link back to a common ancestor ...

Researchers at Linköping University in Sweden made an unexpected discovery while investigating genetically unique women. Their insights advance our understanding of our most enigmatic chromosome, the ...