A new fully automated in vivo screening system (AISS) has been developed to transform drug evaluation by enabling rapid, precise, and non-invasive multi-organ imaging in zebrafish. Integrating cutting ...

Because zebrafish are small and translucent, researchers can image each animal's entire brain to better track the drug's effects. The Ahrens Lab had shown in earlier work that zebrafish exhibit a ...

The preclinical evaluation of drug-induced cardiotoxicity is an important stage in the drug development process; however, ...

they found that the leprosy drug clofazimine reduces the toxicity of polyQ proteins and restores mitochondrial function in zebrafish and worms. The finding supports the previous hypothesis that ...

offering a promising tool for more efficient and reliable drug evaluation. The AISS is designed to automate the entire process of zebrafish larvae handling. Using microfluidic chips, the system ...

A study led by Prof. Liu Feng from the Institute of Zoology of the Chinese Academy of Sciences has identified a crucial role ...

3. Impact of any genetic mutation or drug treatment is easy to see The transparent nature of zebrafish embryos and larvae allows for non-invasive observation of genetic mutations or drug effects, ...

We are a group of Purdue faculty using zebrafish in our research. Our research interest covers a wide variety of topics, including cancer, development, disease modeling, drug discovery, immunology, ...

The effects of antidepressant exposure during early development can pass down through three generations of offspring—at least in zebrafish. A new study ... reuptake inhibitor (SSRI), a class of drugs ...

Yet, the zebrafish model joins us together. Our research interest covers a wide variety of topics, including cancer, development, disease modeling, drug discovery, immunology, neuroscience and ...

EraCal Therapeutics is developing a novel oral-active anti-obesity drug, Era-379, identified using the company’s state-of-the-art, zebrafish-based platform technology. EraCal is raising a series ...

"Zebrafish larvae are particularly suitable ... unwanted cell growth or the targeted treatment of organs with effective drugs. More information: Linda-Marie Mulzer et al, Dynamic changes of ...