Clotting is initiated by two processes or pathways - a slower but larger intrinsic pathway (contact activation pathway) or a very rapid extrinsic pathway (tissue factor pathway) - which lead to ...

When skin is cut or damaged, tiny cell fragments circulating in the blood, called platelets, arrive at the injury and spread ...

Platelet spreading and clot contraction are controlled by different pathways. This discovery leads to safer treatments for ...

Disseminated intravascular coagulation is a bleeding disorder characterized by two seemingly opposite conditions. As a caregiver in a neonatal intensive care unit (NICU), it is not uncommon to ...

Over the last three years, the FDA has approved six new hemophilia drugs, including three gene therapies. | Over the last ...

Until recently, researchers believed that platelet spreading and clot contraction were controlled by the same pathway. However a recent study from Thomas Jefferson University researchers challenges ...