近日，南昌大学研究团队在肝癌治疗领域取得重大突破，这一发现不仅为肝癌患者带来了新的希望，也为全球肿瘤研究领域注入了新的活力。研究团队在国际知名期刊《Cell Death & Disease》上发表了题为“NUB1 reduction promotes PCNA-mediated tumour growth by disturbing the PCNA polyubiquitination/NEDD ...

总之，原发性肝癌的外科治疗目前正朝着微创和精准的方向发展。近年来人工智能、技术创新、治疗理念、临床试验等方面的共同进步，能更加有效地指导HCC手术的临床实践，最终改善肝癌患者的生存预后。

Diffuse midline glioma (DMG), H3K27-altered, is a lethal pediatric high-grade tumor, lacking effective treatment options, ...

研究结论表明，相较于替雷利珠单抗联合安罗替尼的治疗方案，联合放疗能显著延长晚期 HCC 患者的中位 PFS 和 OS，且未出现与放疗相关的不良事件。这意味着 ICIs 联合靶向药物和精准放疗或许是晚期 HCC 安全有效的治疗方案，有望成为未来临床研究和应用的主要方向。不过，该研究也存在一定局限性，如回顾性研究、样本量较小，且未深入探究 PD- (L) 1 状态、肿瘤突变负荷等潜在机制 。但总体而言 ...

Identification of CCNB1 as a biomarker for cellular senescence in hepatocellular carcinoma: a bioinformatics and experimental validation study 为探寻肝细胞癌（HCC）可靠诊断标志物和治疗靶点，安徽医科大学研究人员经生物信息分析和实验，发现 CCNB1 或为 ...

Randomized controlled trials are also needed to determine whether statins can actually reduce the risk for hepatocellular ...

In a UK first, researchers in Manchester are successfully identifying patients in the early, curable stages of a common liver ...

Sunshine Biopharma's K1.1 mRNA-LNP shows promise for HCC treatment in mice, while its 2024 revenue surged 45% to $34.9 ...

Importance of Defining Recurrence in Hepatocellular Carcinoma: Local or Both Local and Other Intrahepatic Recurrences? The following represents disclosure information provided by the author of this ...

An independent data monitoring board found that BeiGene’s ociperlimab was unlikely to significantly boost overall survival in ...

Statins, commonly used to lower cholesterol, may significantly reduce the risk of liver cancer in patients with chronic liver disease, a new study suggests. Researchers found that statin use decreased ...