In addition to cell-cycle regulation, mTOR plays a role in muscle hypertrophy following increased use through the growth factor IGF-1 and tumor suppressor PTEN. Blocking mTOR with drugs like rapamycin ...

Single-cell analysis revealed the molecular triggers that drive stem cells to become cancerous, which may help inform ...

Using breast cancer patient-derived organoids and tumor ... Key changes include reduced activity of mTOR, a metabolic ...

Researchers from SRM Institute of Science and Technology, led by Dr. KN Aruljothi, have published a study in ExRNA highlighting the role of exosomal RNA (exRNA) in head and neck cancers (HNCs).

A team led by Prof. Wuran Wei from West China Hospital of Sichuan University and Dr. Dechao Feng from the Division of Surgery and Interventional Science at University College London has systematically ...

Metastatic breast cancer is complex, requiring holistic care and ongoing treatment, with varying prognosis depending on ...

Promising therapies for platinum-resistant ovarian cancer produced mixed results in separate trials. The AKT inhibitor ...

Everolimus (Afinitor) is a drug that blocks the mTOR protein and helps stop the growth and spread of cancer cells. PI3K inhibitors. Alpelisib (Piqray) and inavolisib (Itovebi) block a type of ...

Audrey Gross; Head of Corporate Communications; Aadi Bioscience Inc. Dave Lennon; President, Chief Executive Officer, Principal Executive Officer; Aadi Bioscience In ...

Scientists at Southern University of Science and Technology in Shenzhen, China, have identified a new regulator of the mammalian target of rapamycin (mTOR) pathway associated with the growth of ...