One of the factors that determine the success of the tetramer production is the binding affinity of the peptide for the MHC class I molecule. Unfortunately, we cannot accurately predict the binding ...

All expression plasmids containing MHC alleles will be retained at our facility and will be used for future production and distribution of tetramer reagents. Requestors incur the cost of peptide that ...

How many naive T cells that are specific for any one peptide–MHC complex exist in an individual? How does that number influence the immune response? Answers to these questions have remained ...