研究人员为探究 PYROXD1 保护 tRNA 连接酶复合物（tRNA-LC）机制，解析相关结构，明确其作用及意义。 在生命的微观世界里，RNA 分子如同忙碌的 “小工匠”，参与着各种重要的生命活动。其中，tRNA（转运核糖核酸）在蛋白质合成过程中起着关键的 “搬运工” 作用 ...

HC Bioscience is shutting down after conducting preclinical models for a transfer RNA (tRNA) asset designed to treat ...

为探究 tRFs 在羊生长发育中的调控作用，宁夏大学的研究人员开展羊皮肤中 tRNA 衍生小 RNAs 差异表达的研究。结果发现其在幼体与成体有显著差异。该研究为羊发育及免疫研究提供新思路，强烈推荐科研读者阅读。 宁夏大学动物科学技术学院（College of Animal ...

Transfer ribonucleic acid (tRNA) is a type of RNA molecule that helps decode a messenger RNA (mRNA) sequence into a protein. tRNAs function at specific sites in the ribosome during translation ...

Boston biotech hC Bioscience shuts down after failed hemophilia A program, CEO Leslie Williams says. Company had raised $40M ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive ...

The Technion researchers' study describes an evolutionary scenario where protection arises from a reduced level of tRNA (transfer RNA), a molecule critical for gene translation. "Studies on ...

Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related mortality worldwide. Current treatment modalities are few or ...

∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001. IARS2, isoleucyl-tRNA synthetase 2; PDAC, pancreatic ductal adenocarcinoma. Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of ...