Lipopolysaccharide (LPS) induction of the gene encoding interleukin 12 p40 requires remodeling of a promoter-encompassing nucleosome and the Toll-like receptor (TLR)–mediated activation of a c ...

This study proposes a new mechanism by which Chd1 senses and responds to DNA unwrapping via EDBL engagement to suppress ...

The cell's genetic material, DNA, is packaged into tightly wound structures called nucleosomes. The DNA (red) is wound around two sets of core histone proteins (green) to form a kind of bead on a ...

The central part of each nucleosome (core particle) is a cylindrical structure (5.7 nanometers in height and 11 in diameter) ...

VolitionRx Limited (NYSE AMERICAN: VNRX) ("Volition"), a multi-national epigenetics company, today announces the publication of "Evaluation of plasma nucleosome concentrations and the effect of ...

A group including Jonathan Widom at Northwestern University and Eran Segal of the Weizman Institute used sophisticated computer modeling along with experimental approaches to uncover DNA-encoded rules ...