MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.
Using cryo-electron microscopy (cryo-EM), a team of structural and molecular biologists at Memorial Sloan Kettering Cancer Center (MSK) set out to investigate G4s -- which have gained attention as ...
Scientists at Forschungszentrum Jülich have now been able to gain fascinating new insights using cryo-electron microscopy. Their work is published in the journal Nature Structural & Molecular ...
The importance of this technology has also been recognized in Thailand, and the first cryo-electron microscope was introduced at Mahidol University last year. In this research, we aim to provide ...
Scientists at the University of Leicester have captured the first detailed "molecular movie" showing DNA being unzipped at the atomic level – revealing how cells begin the crucial process of copying ...
Thanks to the Dubochet Center for Imaging (DCI) at the Universities of Geneva, Lausanne, Bern and the EPFL, we have been able ...
Mitochondria are the powerhouses in our cells, producing the energy for all vital processes. Using cryo-electron tomography, ...
By combining advanced electron microscopy with computational reconstruction algorithms, electron tomography provides unprecedented insights into the internal structure, composition, and properties of ...