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27 天
MEK5/ERK5 通路激活 Hedgehog/GLI 信号:黑色素瘤治疗新曙光
为探究 ERK5 对 HH/GLI 信号的调控,研究人员开展相关研究,发现 MEK5 - ERK5 激活 GLI 转录因子,联合靶向或成创新疗法。 黑色素瘤,作为皮肤癌中最为致命的类型,一旦发展到晚期,患者的预后情况往往不容乐观,如同被死神紧紧扼住咽喉,生命的希望愈发渺茫。
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