In human cells, lipid droplets (LDs) predominantly contain either cholesteryl esters or triacylglycerols. This article ...

Once thought to be little more than blobs of fat inside eukaryotic cells, lipid droplets may in fact provide a first line of defence against invading pathogens, according to evidence published today ...

Lipid accumulation in tumor cells and nearby immune cells promotes immune suppression and therapy resistance in ...

However, some initially responsive tumors still develop recurrences. Researchers studied mouse models and found that TNBC cells that survived treatment accumulated lipid droplets containing Omega-6 ...

in particular the mechanisms and physiology of neutral lipid synthesis and storage in lipid droplets. More broadly the lab studies the mechanisms how cells regulate the abundance of lipids, how they ...

Are there key genes involved in TKI resistance in ccRCC? What mechanisms are associated with this development? A research team, led by Professor Ben Liu from the Department of Urology at the First ...

An Osaka Metropolitan University-led study demonstrated that Cdc42 (cell division cycle 42) plays a crucial role in the formation and maintenance of the morphological characteristics of quiescent ...

Lipid bilayers in mammalian membranes can have a more asymmetric composition than previously thought, new research shows.

Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer - ...